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How To Get Heavy Sounding Breakdowns On Guitar?

I am using an Ibanez RG2EX1, and a Peavey Transtube 112 EFX with an Electro Harmonix Metal Muff distortion pedal and I was wondering how to set it to get really heavy low sounding breakdowns like Parkway Drive or All That Remains. My guitar is usually tuned in Drop C, but occasionally Drop B, and rarely drop D. I've been playing for almost 2 years now and I've recently decided I want a much lower heavier sound so that is why I'm looking to make my breakdowns so heavy sounding. Please help!

This is what i use
Full gain
Bass - 8
Treble - 8
Mid - 3
Keep the bass and treble fairly high and the mid down,mess around those areas

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